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Earnings analysis of drugmakers' quarterly results, in-depth business analysis and the CompePharma View, ten new pieces every day.

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CP+ Earnings analysis
UNITED THERAPEUTICS Corp · UTHR · Third quarter 2026

United Therapeutics Q3: Tyvaso DPI lifts sales 4%, but a $130M R&D charge cuts net income 24%

$832.5 million (+4%)Total revenues, Q3 2026$378.5 million (+13%)Tyvaso DPI net sales$125.3 million (-12%)Nebulized Tyvaso net sales

Revenue reached $832.5 million as Tyvaso DPI and Orenitram grew, but Thymmune-related R&D and a higher tax rate pushed net income down to $258.6 million.

14 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Collegium Pharmaceutical, Inc · COLL · Third quarter 2026

Collegium's Q3: ADHD growth and AZSTARYS offset a pain decline, but profit falls

$216.3 million, up 3% year over yearProduct revenues, net (Q3 2026)$51.9 million, up 24% year over yearJORNAY PM net revenue$26.5 millionAZSTARYS net revenue

Record $216.3M revenue rose 3% as JORNAY PM and AZSTARYS filled much of the gap left by pain declines; adjusted EBITDA fell 9% and guidance was reaffirmed.

13 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
iRhythm Holdings, Inc. · IRTC · Third quarter 2026

iRhythm's Q3: Volume-led growth and 23.1% adjusted EBITDA margin, masked by a $49.8M litigation charge

$221.6 million, a 14.9% increase compared to third quarter 2025Q3 2026 revenue74.2%, a 310-basis point increase compared to third quarter 2025Gross margin$51.2 million and 23.1%, respectivelyAdjusted EBITDA / margin

Revenue rose 14.9% to $221.6 million and adjusted EBITDA margin hit 23.1%, but GAAP losses widened on settlements as the VitalConnect deal closed and guidance rose.

13 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Obsidian Therapeutics, Inc. · OBX · Third quarter 2026

Obsidian's first quarter as a public company: $324.4M cash, a widening loss and a 2027 readout

$50.7 million, or $1.23 per basic and diluted shareQ3 2026 net loss$324.4 millionCash, equivalents and marketable securities (Sept 30, 2026)into 2H 2028Expected cash runway

Obsidian Therapeutics posted a $50.7M Q3 net loss after its Galera deal and $350M financing, with its amsoki-cel registration-enabling cohort now the main driver of value.

13 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Tarsus Pharmaceuticals, Inc. · TARS · Third quarter 2026

Tarsus's XDEMVY hits $194.6M as $632.2M of acquired IPR&D drives a $668.3M loss

$194.6 millionQ3 2026 XDEMVY net product salesapproximately 64%Year-over-year growth$632.2 millionAcquired IPR&D expense

Tarsus reported 64% year-over-year growth for XDEMVY and a roughly 93% gross margin, while two acquisitions pushed the quarter deep into the red and reshaped the pipeline.

12 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Xeris Biopharma Holdings, Inc. · XERS · Third quarter 2026

Xeris Q3: Recorlev Now Drives the Story as the Company Lifts 2026 and 2030 Revenue Targets

$107.2 million (+44% YoY)Q3 total revenue$71,540 thousand (+93%)Q3 Recorlev net revenue88% (vs 85%)Q3 gross margin

Recorlev's 93% jump more than accounted for Xeris's 44% revenue growth in Q3, while Gvoke shrank and the company raised both its 2026 guidance and its 2030 outlook.

12 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Tg Therapeutics, Inc. · TGTX · Third quarter 2026

TG Therapeutics lifts 2026 guidance to ~$1B as BRIUMVI growth meets a 2027–28 dosing pivot

$259.9 millionQ3 2026 total global revenue$232.6 million (approx. 52% increase over the same period last year)Q3 BRIUMVI U.S. net product revenueapproximately $1 billion, from approximately $950 millionFY2026 total global revenue guidance

A Q3 beat-and-raise on BRIUMVI's U.S. business sets up a run of dosing-format catalysts, from subcutaneous Phase 3 data to a simplified IV start, while spending rises.

12 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Charles River Laboratories International, Inc. · CRL · Third quarter 2026

Charles River's Q3: DSA Volume and Divestiture Mix Lift Margins, Guidance Raised

$982.7 million (-2.2% reported)Q3 revenue4.7%Organic revenue growth$3.09 (+27.2%)Non-GAAP EPS

Organic revenue rose 4.7% as safety assessment volume and Manufacturing demand offset May divestitures; the company lifted 2026 revenue and non-GAAP EPS guidance.

11 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Biomarin Pharmaceutical Inc · BMRN · Third quarter 2026

BioMarin tops $1B a quarter on Amicus, but order timing and IPR&D charges cut 2026 guidance

$1,025 million (+32% Y/Y)Q3 2026 total revenues$744 million (+44% Y/Y)Metabolic Conditions revenue$245 million (+12% Y/Y)VOXZOGO revenue

Revenue rose 32% to $1.025 billion in Q3, yet lumpy international orders and two acquired-R&D charges led the company to lower full-year revenue and non-GAAP EPS guidance.

11 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Harmony Biosciences Holdings, Inc. · HRMY · Q1 2027

Harmony's WAKIX grows 12% to $268.9M, but royalties and milestones squeeze profit

$268.9 million (vs $239.5 million; +12%)Q3 WAKIX net revenue9,350 (+400 in Q3)Estimated average patients30% (vs 25%)Cost of product sold, % of net revenue

Q3 demand stayed solid with 400 net patient adds and full-year guidance was held, while higher royalties and an R&D milestone cut earnings and the 2027 legal and regulatory calendar looms.

11 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Madrigal Pharmaceuticals, Inc. · MDGL · Third quarter 2026

Madrigal's Rezdiffra posts first profitable quarter as SG&A growth lags sales

$431.3 million (+50% vs $287.3 million)Q3 2026 Rezdiffra net sales$55.4 million ($1.83 per diluted share)Q3 2026 net income$375.3 million (vs $401.2 million)Q3 2026 operating expenses

Third-quarter net sales of $431.3 million, up 50%, turned a $114.2 million loss into $55.4 million of net income, while the company is already investing for the cirrhosis market.

10 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Ani Pharmaceuticals Inc · ANIP · Third quarter 2026

ANI's Cortrophin guidance cut tempers a strong Q3 as Egetis deal pivots to rare disease

$290.8 million, +27.6% year-over-yearQ3 total net revenues$138.7 million, +36.1%Cortrophin Gel net revenues$83.3 million, +39.8%Adjusted non-GAAP EBITDA

ANI beat on growth and profit in Q3, but cut Cortrophin Gel guidance by $40 million at both ends, blaming specialty pharmacy capacity, while launching a roughly $560 million bid for Egetis.

10 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Krystal Biotech, Inc. · KRYS · Third quarter 2026

Krystal's VYJUVEK Hits $127.3M, but Net Income Slips as Pipeline Timelines Stretch

$127.3 millionQ3 2026 net product revenue30%Growth vs Q3 202594%Q3 gross margin

VYJUVEK revenue rose 30% to $127.3M with a 94% gross margin, and Krystal authorized a $400M buyback, yet net income fell year on year and several readouts moved into 2027.

10 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Corcept Therapeutics Inc · CORT · Third quarter

Corcept's Lifyorli adds $91.4M in Q3 as profit surges and guidance is held

$340.5 millionQ3 2026 revenue$91.4 millionLifyorli product revenue$249.1 millionKorlym and authorized generic revenue

Corcept's third-quarter revenue rose 64% to $340.5M as Lifyorli nearly doubled sequentially, but reiterated 2026 guidance of $1.1–1.2B leaves a wide range for Q4.

09 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Ironwood Pharmaceuticals Inc · IRWD · Full year 2026

Ironwood lifts 2026 guidance again as LINZESS profit share and lower SG&A widen margins

$133,040 thousand (vs $122,060 thousand in Q3 2025)Q3 2026 total revenue$324.9 million, +3.2%Q3 LINZESS U.S. net sales$59,838 thousand ($0.36 per share basic and diluted)Q3 GAAP net income

Q3 revenue of $133 million and record adjusted EBITDA of $98 million came with a second guidance raise, while quarterly LINZESS sales growth slowed to 3.2% on rebate reserves.

09 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Acadia Pharmaceuticals Inc · ACAD · Third quarter 2026

Acadia's DAYBUE surge lifts Q3 revenue 23%, but a tax swing and heavier SG&A cut net income

$342 million, up 23% vs. GAAP $279 million in Q3 2025Q3 2026 total revenues$140 million, up 39% from $101 millionDAYBUE net sales$202 million, up 14% (up 12% vs. non-GAAP adjusted $180 million)NUPLAZID net sales

Acadia raised 2026 DAYBUE guidance to $505–$520 million as DAYBUE STIX drove growth, while lower R&D spending and a swing from a tax benefit to a tax charge shaped the bottom line.

09 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Sarepta Therapeutics, Inc. · SRPT · Third quarter 2026

Sarepta's PMO franchise carries Q3 as ELEVIDYS shrinks and DM1/FSHD data loom

approximately $323.8 millionQ3 net product revenuesapproximately $240.3 millionPMO net product revenues$83.5 millionELEVIDYS net product revenue

Net product revenue of $323.8M and a non-GAAP operating profit of $22.9M came with a higher guidance floor, while Q4 DM1 and FSHD readouts will shape the pipeline story.

08 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Moderna, Inc. · MRNA · Third quarter 2026

Moderna's Q3 swing to profit rests on international COVID deliveries and a $3.0B notes deal

$1,313 million (+29% vs. $1,016 million)Q3 2026 total revenue$162 million vs. net loss of $(200) millionQ3 GAAP net income$0.38 vs. $(0.51)Q3 diluted EPS

Revenue rose 29% to $1.3 billion and the company raised its 2026 outlook, but the quarter's receivables, the convertible financing and a flu launch constrained by contracting timing shape the story.

08 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Halozyme Therapeutics, Inc. · HALO · Third quarter 2026

Halozyme's Royalty Engine Lifts Guidance as Patent Win and Deal Flow Widen the Moat

$493.0 million (up 39% YOY)Q3 total revenue$341.0 million (up 44% YOY)Q3 royalty revenue$336.2 million vs $248.2 millionQ3 adjusted EBITDA

Third-quarter revenue rose 39% to $493.0 million on 44% royalty growth, and Halozyme raised all four 2026 guidance ranges while securing a Dutch injunction against Merck's Keytruda Qlex.

08 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Prothena Corp Public Ltd Co · PRTA · Third quarter 2026

Prothena's Q3: Costs Fall, Partners Carry the Pipeline, and Cash Burn Stays Low

$16.5 million (vs $36.5 million in Q3 2025)Q3 2026 net loss$0.6 million (vs $2.4 million)Q3 2026 total revenue$52.7 million (vs $9.7 million)Nine-month 2026 total revenue

A $50.0 million Novo milestone flattered nine-month results, but the Q3 story is a much smaller cost base and a pipeline now funded by Roche, Novo and Bristol Myers Squibb.

07 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Viatris Inc · VTRS · Third quarter 2026

Viatris holds revenue flat in Q3, lifts guidance midpoints as Nashik halt looms over Q4

$3,749.5 million (vs $3,759.9 million)Q3 total revenues$1,195.7 million, up 4%Q3 adjusted EBITDA$0.71, up 6%Q3 adjusted EPS

Greater China and new products offset supply constraints and generics erosion, and margins widened, but a GAAP tax-driven loss and a suspended Indian plant frame the Pacira-era story.

07 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Protagonist Therapeutics, Inc · PTGX · Third quarter 2026

Protagonist's Q3 swings to a $220M profit on Takeda payments; royalty story still ahead

$274,410 thousand (vs $4,712 thousand in Q3 2025)Q3 2026 license and collaboration revenue$220,015 thousand (vs net loss of $39,339 thousand)Q3 2026 net income$3.32 / $3.07Q3 2026 EPS, basic / diluted

A $275 million Takeda trigger on the MIMRYLO approval turned a $39.3 million loss into $220.0 million of net income, while ICOTYDE's royalty contribution is not broken out.

07 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
BeOne Medicines Ltd. · ONC · Third quarter 2026

BeOne's Q3: BRUKINSA drives 34% growth and wider margins, but guidance implies a softer Q4

$1,889,815 thousand (+34%)Q3 total revenue$1.4 billion (+34%)BRUKINSA global sales$3.28 / $4.59GAAP / non-GAAP diluted EPS per ADS

BeOne raised 2026 revenue guidance to $6.9-$7.0 billion on a quarter in which GAAP operating income rose 157%, with BRUKINSA's MANGROVE filing and ASH data the next catalysts.

06 Nov 2026 · CompePharma editorial
CP+ Earnings analysis
Jazz Pharmaceuticals plc · JAZZ · Third quarter 2026

Jazz's record $1.2B quarter masks a $754M Actio charge as Ziihera launch begins

$1,243.0 million (+10% YoY)3Q26 total revenues$482.8 million (+12% YoY)Xywav net sales$(483.4) million3Q26 GAAP net loss

Third-quarter revenue rose 10% and full-year guidance moved up, but acquired IPR&D pushed Jazz to a GAAP loss as Xywav, Zepzelca and new launches offset a soft Epidiolex.

06 Nov 2026 · CompePharma editorial